C-PLEASURE was a double-blind, three-way randomized crossover trial to address two main issues: (1) male condoms are underutilized largely due to reduced experiences of pleasure; and (2) no condoms are currently indicated for anal sex. For the first issue, we examined perceptions of pleasure and overall condoms use for three types of condoms (fitted, thin and standard condoms) and for the second issue, we assessed condom failure (slippage and breakage) among condoms used for anal sex.